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Long term effects of AAP's

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Long term effects of AAP's

Postby christie on Sun Aug 24, 2008 1:24 pm

Does anyone know about the long-term effects of taking AAP's (spec. Abilify)? I am a little scared of ending up with diabetes or something from taking it.
christie
 

Re: Long term effects of AAP's

Postby HAL 2000 on Mon Aug 25, 2008 5:30 pm

AAP's are a new class of drugs and new ones are coming all the time, so it's hard to say what the long-term effects of them are. Some say diabetes, some Tardive Diskenisia. Unfortunately we are the guinea pigs.

If you worry about diabetes, make sure your doctor make the appropriate tests once in a while. I dug up some info on AAP's, diabetes and schizophrenic patients, and to quote;
The result was that over 4 percent of the patients developed diabetes which is nearly 10 times more than the general population. However, they were only barely able to note a statistical difference between medications in their liability towards causing diabetes. Only clozapine and olanzapine showed an increased risk of diabetes compared to the general group. The authors concluded that those medications did confer an increased risk, but a small one and attributed the overall increased risk of diabetes to other aspects of schizophrenia that have yet to be fully described but could be overall poor diet, poor medical care followup, low socioeconomic status and low exercise amounts.


Make sure you read the rest of it here.
HAL 2000
 

Re: Long term effects of AAP's

Postby MGMT on Wed Aug 27, 2008 10:03 am

And as for tardive dyskinesia, I found this info from Rxlist about the chances of getting tardive dyskinesia from Abilify:
≥ 1/1000 patients and < 1/100 patients -speech disorder, parkinsonism, memory impairment, cogwheel rigidity, cerebrovascular accident, hypokinesia, tardive dyskinesia, hypotonia, myoclonus, hypertonia, akinesia, bradykinesia;

This means that less than 1/100, but more than 1/1000 get it from taking Abilify. Which isn't that much. It's always about weighing the pros and cons, but Abilify isn't your worst choice.
Diagnosis: schizotypal disorder, depression
Meds: Abilify 20 mg
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